Table 1 of
Davoudi, Mol Vis 2018; 24:59-74. Table 1 of
Davoudi, Mol Vis 2018; 24:59-74.
Table 1. 38 SNPs previously associated with sarcoidosis, sarcoidosis severity or organ-specific sarcoidosis involvement.
| Gene Name or Locus | SNP | Reference | Association with |
|---|---|---|---|
| ANXA11 | rs2789679* | Hofmann et al. 2008 [12] | Sarcoidosis |
| ANXA11 | rs2573346* | Hofmann et al. 2008 [12] | Sarcoidosis |
| ANXA11 | rs1049550* | Hofmann et al. 2008 [12] | Sarcoidosis |
| ANXA11 | rs61860052 | Levin et al. 2012 [22] | Sarcoidosis in African Americans |
| ANXA11 and PLAC9 | rs1953600* | Hofmann et al. 2008 [12] | Sarcoidosis |
| BTNL2 | rs9268480* | Adrianto et al. 2012 [6] | Sarcoidosis |
| BTNL2 (upstream) | rs9268482* | Adrianto et al. 2012 [6] | Sarcoidosis |
| CDCC88B | rs671976* | Fischer et al. 2012 [14] | Sarcoidosis |
| CDCC88B | rs479777* | Fischer et al. 2012 [14] | Sarcoidosis |
| CCR 5 | rs1799987 | McDougal et al. 2009 [36] | Erythema nodosum in sarcoidosis |
| CCR 5 | rs333 | Fischer et al. 2008 [37] | Lofgren syndrome |
| Locus 1q24.3 | rs12035082 | Fischer et al. 2011[38] | Acute sarcoidosis |
| CFH Y402H | rs1061170 | Thompson et al. 2013 [18] | Ocular sarcoidosis |
| C10ORF67/10p12.2 | rs1398024* | Franke et al. 2008 [39] | Sarcoidosis |
| HERC2 | rs916977 | Fischer et al. 2011 [38] | Sarcoidosis |
| IL23R | rs11465804 (intron 8) | Kim et al. 2011 [20] | Sarcoidosis, Sarcoidosis-associated uveitis |
| IL23R | rs75117847 (intron 6) | Kim et al. 2011 [20] | Sarcoidosis |
| HSP-70/Hom | rs2075800 | Spagnolo et al. 2007 [19] | Sarcoidosis-associated uveitis |
| HSP-70/Hom | rs1043620 | Spagnolo et al. 2007 [19] | Sarcoidosis |
| IL23R | rs11209026 | Fischer et al. 2011 [20, 38] | Chronic sarcoidosis |
| IL2RA | rs12722489† | Zhou et al. 2012 [40] | Complicated sarcoidosis |
| LTA | rs909253 | McDougal et al. 2009 [36] | Erythema nodosum in sarcoidosis |
| NOTCH4 | rs715299* | Adrianto et al. 2012 [6] | Sarcoidosis |
| OS9 | rs11172300* | Hofmann et al. 2013 [13] | Sarcoidosis |
| OS9 | rs701007*† | Hofmann et al. 2013 [13] | Sarcoidosis |
| OS9 | rs799265*† | Hofmann et al. 2013 [13] | Sarcoidosis |
| RAB23 | rs1040461* | Hofmann et al. 2011 [26] | Sarcoidosis |
| TGF-β2 | rs1891467 | Kruit et al. 2006 [41] | Pulmonary fibrosis in sarcoidosis |
| TGF-β3 | rs3917200 | Kruit et al. 2006 [41] | Pulmonary fibrosis in sarcoidosis |
| TGF-β3 | rs3917165 | Kruit et al. 2006 [41] | Pulmonary fibrosis in sarcoidosis |
| TLR4 | rs4986790 | Pabst et al. 2006 [16] | Chronic sarcoidosis |
| TNF-α | rs1800629 | McDougal et al. 2009 [36] | Erythema nodosum in sarcoidosis |
| HLA- DQA1 | rs17843604* | Adrianto et al. 2012 [6] | Sarcoidosis |
| HLA- DQB1 | rs149288329* | Adrianto et al. 2012 [6] | Sarcoidosis |
| HLA- DRA | rs7192* | Adrianto et al. 2012 [6] | Sarcoidosis |
| HLA- DRA | rs7194* | Adrianto et al. 2012 [6] | Sarcoidosis |
| HLA- DRB1 | rs615672* | Adrianto et al. 2012 [6] | Sarcoidosis |
| HLA- DRB5 | rs17203612* | Adrianto et al. 2012 [6] | Sarcoidosis |