Figure 4. The loss of microglia and Pax6-positive retinal precursor cells in Grn−/− mice. A: Progranulin (magenta) is not observed in the Grn−/− retina at P7. The number of Iba-1-positive microglia (green) is decreased in Grn−/− mice. B: The retinal precursor cell marker, Pax6 (red), is decreased in Grn−/− mice. Data are the mean ± standard error of the mean (SEM; n=5 or 6). #p<0.05 versus wild type (Student t test). Scale bar=20 μm.