Figure 8 of Hollborn, Mol Vis 2018; 24:518-535.

Figure 8. Effects of (A) knockdown of C9 with siRNA and (B) the administration of C9 protein on the cytosolic level of mature IL-1β. The cells were stimulated with a hyperosmotic medium (+ 100 mM NaCl) for (A) 6 h and (B) 24 h. The IL-1β level was measured with ELISA and is expressed as percent of unstimulated control (100%). A: The cells were transfected with nontargeted siRNA (siNon; 10 nM) and C9 siRNA (siC9; 10 nM). B: The cells were cultured in the absence and presence of C9 protein (10 nM). The numbers of independent experiments using cell lines from different donors are indicated in the bars. Significant difference versus unstimulated control: *p<0.05. Significant difference versus siNon: ●p<0.05. Significant difference versus NaCl control: ○p<0.05.