Table 4 of
Daull, Mol Vis 2018; 24:459-470. Table 4 of
Daull, Mol Vis 2018; 24:459-470.
Table 4. Effects of the alkyl chain length on PKC inhibition of various alkyl benzyl derivatives.
| Alkyl chain length | IC50 (µM) | |||
|---|---|---|---|---|
| PKCα | PKCβ1 | PKCβ2 | PKCδ | |
| C8 | - | - | - | - |
| C10 | >128.2 | - | - | >128.2 |
| C12 | 22.6 | 58.8 | 58.8 | >117.6 |
| C14 | 5.4 | 10.1 | 14.1 | >108.7 |
| C16 (CKC) | 4.3 | - | - | - |
| C18 | 11.7 | 74.6 | 39.3 | - |