Figure 4. Chromatograms showing three novel variants identified in patients with 
CRD. A: Sequence trace of the PRPH2 gene (fragment of exon 2) in 
the affected individual (Family 9) carrying a heterozygous missense variant 
c.592A>C (upper panel) and a normal control individual (lower panel). B: 
Sequence trace of the PROM1 gene (fragment of exon 14) in the affected individual 
(Family 5) carrying the heterozygous frameshift change c.1612delT (upper panel) 
and a normal control individual (lower panel). C: Sequence trace of the PROM1 
gene (fragment of exon 23) in the affected individual (Family 5) carrying the 
heterozygous frameshift change c.2389dupG (upper panel) and a normal 
control individual (lower panel). Because the RPGR-ORF15 gene was sequenced commercially by Asper Biotech (Tartu, Estonia), the chromatogram is not available. The chromatogram showing the mutation c.1691A>G in the ATF6 gene was included in our previous report [19].