Molecular Vision: Musolf, Mol Vis 2018; 24:29-42. Table 1

Table 1. Variants that exhibit genome-wide significant and suggestive evidence of linkage to myopia from the collapsed haplotype pattern linkage analysis.

CHR	HLOD	ALPHA	LOD	POS	GENE
10q26.13	3.73	1.00	3.73	146.7658	TACC2
10q26.2	2.77	1.00	2.77	156.932	DOCK1
15q13.3	2.64	0.87	2.42	27.82131	RYR3
9q31.3	2.58	1.00	2.58	117.7108	SVEP1
9q33.2	2.53	1.00	2.53	131.6962	CDK5RAP2
1p13.1	2.49	1.00	2.49	40.94913	IGSF21
10q25.3	2.41	1.00	2.41	133.0324	VWA2
10q24.31	2.34	1.00	2.34	119.6265	CWF19L1
10q26.11	2.15	1.00	2.15	141.0359	EIF3A
10q24.2	2.08	1.00	2.08	119.2729	ABCC2
15q15.2	2.04	1.00	2.04	42.58454	STARD9
12q24.13	2.03	1.00	2.03	129.8192	CCDC42B
1p31.3	1.98	1.00	1.98	94.08912	INADL
11q22.3	1.97	1.00	1.97	113.0644	EXPH5
12q23.2	1.94	1.00	1.94	117.4295	IGF1
12q24.13	1.94	1.00	1.94	129.8897	IQCD
6q15	1.92	1.00	1.92	99.52311	GABRR1

Table displaying the genome-wide significant and suggestive linkage signals from the collapsed haplotype pattern (CHP) variant two-point linkage analysis sorted by heterogeneity LOD (HLOD). CHP variants are multi-allelic pseudo-markers corresponding to a gene and created from SNPs with a MAF <0.15. The genome-wide significance threshold is 3.3 and the genome-wide suggestive threshold is 1.9, as recommended by Lander and Kruglyak. CHR=chromosomal region, HLOD=heterogeneity LOD score of the marker, ALPHA=estimated proportion of informative families showing evidence of linkage for each HLOD, LOD=cumulative LOD across all families, POS=position in cM of the gene, GENE=Gene location of the CHP marker.