Figure 3. Pedigrees of the Rb family cases. A: c.1960G>A mutation causing a splice-site variation in the siblings patient RB15 and patient RB24. B: c.1494T>G heterozygous mutation of patient RB35 and c.1494T>G mosaic mutation of patient RB35’s mother. C: c.1939–1940delTC causing a frameshift mutation in patient RB45. Solid black and half-black symbols represent bilateral and
unilateral Rb, respectively. The symbol with a black dot represents an unaffected mutation carrier.