Figure 3. Single base resolution view of the human
RHO promoter (top) and RER (bottom) in the UCSC Genome Browser’s hg38 human genome assembly aligned with five other vertebrate
species. The experimentally validated CRX binding sites RET-1 and BAT-1 [
17] in the promoter region and RHBS-1 and Ret-3 [
53] in the enhancer region are indicated with light blue highlighting. The sequence used in the CRX/promoter binding simulations
is indicated as a black custom track.