Figure 6. The expression levels of IFN-related inflammatory cytokines in the control, voriconazole, and voriconazole plus FK506 groups in fungal keratitis. The mRNA expression levels of interferon (IFN)-related inflammatory cytokines (interleukin (IL)-1α, IL-6, IL-12, and IL-17; A to D; normalized to β-actin) and the protein levels and band intensity of the pro- and mature form of IL-1α (E and F) in the voriconazole and voriconazole plus FK506 groups decreased gradually after fungal infection. The data are the mean ± standard error of the mean (SEM) and represent three individual experiments with six animals/group/time. *, p<0.05; **, p<0.01; ***, p<0.001.