Table 2 of
Shah, Mol Vis 2018; 24:127-142. Table 2 of
Shah, Mol Vis 2018; 24:127-142.
Table 2. Most strongly associated marker in each region in the GWAS meta-analysis of all samples (Europeans and Asians of all ages combined).
| SNP | Chr | Pos | Effect allele | Other allele | EAF | OR (95%CI) | P value | Nearest gene |
|---|---|---|---|---|---|---|---|---|
| rs7673984 | 4 | 55,088,761 | T | C | 0.22 | 1.12 (1.08–1.16) | 5.55×10−9 | PDGFRA |
| rs34751092 | 4 | 24,129,037 | A | G | 0.28 | 1.09 (1.05–1.13) | 6.07×10−7 | PPARGC1A |
| rs630203 | 5 | 141,444,269 | T | G | 0.74 | 0.92 (0.88–0.95) | 8.83×10−7 | MRPL11P2 |
| rs75607298 | 8 | 128,611,496 | A | G | 0.72 | 1.14 (1.08–1.21) | 2.28×10−6 | CASC11 |
| rs62401199 | 6 | 43,813,341 | T | C | 0.14 | 1.15 (1.09–1.22) | 3.29×10−6 | LINC01512 |
| rs753992 | 11 | 47,349,846 | A | G | 0.29 | 0.91 (0.87–0.95) | 3.48×10−6 | MADD |
| rs3214101 | 11 | 114,009,408 | A | T | 0.68 | 1.08 (1.05–1.12) | 3.75×10−6 | ZBTB16 |
| rs10985068 | 9 | 123,629,724 | C | G | 0.12 | 1.13 (1.07–1.19) | 5.87×10−6 | PHF19 |
| rs62128379 | 2 | 26,960,055 | T | C | 0.85 | 1.13 (1.07–1.19) | 6.00×10−6 | KCNK3 |
| rs9939114 | 16 | 84,023,972 | A | G | 0.05 | 0.54 (0.41–0.70) | 6.01×10−6 | NECAB2 |
| rs60083876 | 7 | 34,228,819 | A | T | 0.95 | 1.31 (1.17–1.48) | 6.53×10−6 | BMPER |
| rs859362 | 1 | 175,495,090 | T | C | 0.19 | 1.10 (1.05–1.15) | 7.14×10−6 | TNR |
| rs11775037 | 8 | 108,317,615 | A | G | 0.20 | 1.10 (1.05–1.14) | 7.31×10−6 | ANGPT1 |
| rs7036824 | 9 | 96,149,894 | T | C | 0.94 | 0.83 (0.77–0.90) | 8.78×10−6 | C9orf129 |
| rs142168171 | 7 | 71,253,651 | I | R | 0.09 | 1.37 (1.19–1.57) | 9.14×10−6 | CALN1 |
| rs7278671 | 21 | 41,047,876 | A | G | 0.51 | 0.93 (0.90–0.96) | 9.31×10−6 | B3GALT5 |
| rs191640722 | 1 | 119,264,997 | C | G | 0.09 | 0.87 (0.82–0.93) | 9.53×10−6 | LOC100421281 |
| rs36107906 | 2 | 44,162,800 | D | R | 0.29 | 1.09 (1.05–1.13) | 9.61×10−6 | LRPPRC |
| rs4896367 | 6 | 138,807,281 | T | C | 0.72 | 1.09 (1.05–1.14) | 9.75×10−6 | NHSL1 |
| rs35587414 | 1 | 153,174,958 | T | C | 0.15 | 1.13 (1.07–1.20) | 9.79×10−6 | LELP1 |