Table 1 of
Shah, Mol Vis 2018; 24:127-142. Table 1 of
Shah, Mol Vis 2018; 24:127-142.
Table 1. Subject demographics of participating CREAM study groups.
| Study | Ancestry | N (cases/controls) | %Female | Age (years) | Corneal astigmatism (D) | |
|---|---|---|---|---|---|---|
| Mean (SD) | Median (IQR) | Range | ||||
| ALSPAC | European | 2279(985/1294) | 53.1 | 15.5 (0.3) | 0.683 (0.469–0.959) | 0.000–5.680 |
| BMES | European | 1238(720/518) | 41.8 | 73.3 (7.6) | 0.863 (0.565–1.295) | 0.155–8.615 |
| EPIC | European | 857(456/401) | 58.5 | 68.7 (7.4) | 0.780 (0.527–1.152) | 0.075–3.997 |
| FITSA | European | 127(62/65) | 100 | 67.9 (3.1) | 0.733 (0.530–1.033) | 0.270–2.020 |
| GenerationR | European | 2071(981/1090) | 49.9 | 6.09 (0.4) | 0.725 (0.480–0.995) | 0.000–3.370 |
| GHS 11 | European | 2398(1003/1395) | 48.7 | 55.9 (10.8) | 0.65 (0.400–0.950) | 0.050–4.350 |
| GHS 21 | European | 851(383/468) | 50.9 | 55.1 (10.8) | 0.65 (0.450–1.000) | 0.050–3.800 |
| RAINE | European | 1028(407/621) | 50.9 | 20.0 (0.4) | 0.649 (0.445–0.905) | 0.280–2.440 |
| Rotterdam-I | European | 5537(2064/3473) | 59.3 | 69.5 (9.2) | 0.601 (0.334–1.007) | 0.000–9.663 |
| Rotterdam-II | European | 1982(633/1349) | 53.8 | 64.8 (8.0) | 0.539 (0.294–0.884) | 0.000–6.789 |
| Rotterdam-III | European | 2925(1180/1745) | 56.2 | 57 (6.9) | 0.618 (0.356–1.019) | 0.000–4.869 |
| OGP-A2 | European | 92(37/55) | 44.6 | 16.0 (4.5) | 0.682 (0.512–0.942) | 0.185–3.070 |
| OGP-B2 | European | 446(181/265) | 43.7 | 50.6 (15.4) | 0.650 (0.430–0.970) | 0.130–4.240 |
| TwinsUK | European | 419(201/218) | 92.7 | 64 (10.5) | 0.729 (0.476–1.105) | 0.000–5.432 |
| BES-610K3 | Asian | 553 (240/313) | 65.6 | 62.1 (8.4) | 0.666 (0.407–1.056) | 0.000–3.620 |
| BES-OmniE3 | Asian | 469 (208/261) | 60.1 | 64.7 (9.5) | 0.676 (0.429–1.016) | 0.000–5.082 |
| SCES-610K3 | Asian | 1745 (787/958) | 48.7 | 57.6 (9.0) | 0.703 (0.476–1.060) | 0.109–5.868 |
| SCES-OmniE3 | Asian | 545 (257/288) | 48.6 | 59.2 (8.8) | 0.723 (0.470–1.065) | 0.117–5.404 |
| SCORM | Asian | 947 (768/179) | 48.6 | 10.8 (0.8) | 1.205 (0.851–1.624) | 0.138–3.911 |
| SIMES | Asian | 1778 (750/1028) | 51.7 | 59.5 (10.8) | 0.662 (0.432–1.016) | 0.078–5.618 |
| SINDI | Asian | 2261 (814/1447) | 48.6 | 56.5 (9.1) | 0.614 (0.411–0.912) | 0.115–4.727 |
| STARS | Asian | 822 (525/297) | 50.0 | 38.5 (5.3) | 1.000 (0.625–1.380) | 0.125–3.875 |