Table 2 of Donahue, Mol Vis 2017; 23:987-1005.

Table 2. Highly represented genes between optic nerve injury (ONI) and CNS neurodegenerative disease (ND) data sets are listed.

Gene Average FC (Min - Max) Associated GO Terms
C1QB 3.68 (1.99–12.58) Complement Activation, Innate Immune Response
CD68 3.55 (1.80–13.15) Cellular Response to Organic Substance
CP 3.13 (1.36–12.73) Ferroxidase Activity, Cellular Iron Ion Homeostasis, Aging
CSF1R 2.71 (1.52–10.91) Inflammatory Response, Cellular Proliferation, Axon Guidance
CTSS 3.85 (1.47–18.95) Toll-Like Receptor Signaling Pathway, Antigen Processing and Presentation, Extracellular Matrix Dissassembly
DECR1 1.63 (1.18–2.55) NADPH Binding, Protein Homotetramerization
DUSP15 1.63 (1.18–2.10) Transforming Growth Factor Beta Receptor Signaling Pathway, Positive Regulation of JNK Cascade
HLA-A 2.85 (1.47–7.67) Immune Response, Antigen Processing and Presentation of Peptide Antigen via MHC class I
LAPTM5 2.52 (1.54–5.63) Protein Binding, Transport
LY86 2.78 (1.44–11.51) Apoptotic Process, Innate Immune Response
MPEG1 3.24 (1.49–15.53) Integral Component of Membrane
MSN 1.91 (1.21–3.73) Leukocyte Cell-Cell Adhesion, Leukocyte Migration
SERPINA3 6.19 (1.48–12.92) Inflammatory Response, Acute Phase Response, Platelet Degranulation
SESN3 1.55 (1.14–2.55) Cellular Response to Amino Acid Stimulus, Negative Regulation of TORC1 signaling, Regulation of Response to Reactive Oxygen Species
TYROBP 3.00 (1.79–12.05) Cellular Defense Response, Intracellular Signal Transduction, Innate Immune Response