Table 1 of
Donahue, Mol Vis 2017; 23:987-1005. Table 1 of
Donahue, Mol Vis 2017; 23:987-1005.
Table 1. Enriched GO terms for DE genes found in both acute and chronic optic nerve injury data sets.
| GO Term | ES | Genes |
|---|---|---|
| Regulation of Cell Migration | 6.28 | RAP2A, RRAS2, MSN, STAT3, CSF1R, SULF1, CORO1A, RRAS, AIF1, EDN2 |
| Intracellular Signal Transduction | 4.23 | MOV10, RAP2A, RRAS2, RAB20, GNAI2, STAT3, RHOC, CSF1R, PSMB8, RRAS, PRDX4, TYROBP, COL1A2, AIF1, EDN2, TNFRSF1A |
| Regulation of Response to Stimulus | 2.67 | LY86, RAP2A, GNAI2, B2M, C1QB, BIRC5, STAT3, RHOC, SESN3, CSF1R, SULF1, PSMB8, SOX2, RRAS, DUSP16, TYROBP, COL1A2, TULP3, AIF1, EDN2, CTSS, TNFRSF1A, HLA-A |
| Depleted | ||
| GO Term | ES | Genes |
| Neurofilament Bundle Assembly | >100 | NEFM, NEFL, NEFH |
| Response to Amine | 33.65 | PPP3CA, NME1, ARG1, KCNC1, CALM1 |
| Synapse Organization | 15.14 | SNCB, RAB3A, SNCG, CACNB4, ATP2B2, CACNG2, NRXN3, NRXN1, UNC13B, |
| Neurotransmitter Secretion | 14.52 | CPLX1, RAB3A, GAD1, NRXN3, NRXN1, UNC13B |
| Regulation of Cation Channel Activity | 13.68 | FGF12, CACNB4, RASGRF1, CACNG2, NRXN1, CALM1 |
| Modulation of Synaptic Transmission | 11.5 | GRM1, SLC6A1, RAB3A, CLSTN1, PPP3CA, GNAI2, SNCG, RASGRF1, GRM8, ATP2B2, NRXN1, UNC13B |
| Axon Development | 7.02 | CRMP1, EPHA5, RAB3A, NEFM, NEFL, CTNNA2, NEFH, KIF5C, NRXN3, NRXN1 |
| Neuron Projection Morphogenesis | 6.11 | CRMP1, EPHA5, NRN1, RAB3A, NEFL, CTNNA2, NEFH, KIF5C, NRXN3, NRXN1 |
| Brain Development | 6.08 | EPHA5, NME1, SLC6A17, ATP2B2, OGDH, KCNC1, NEFL, CTNNA2, NDRG4, PITPNM1, INA, ATP2B2, HPCA, NRXN1, CALM1 |
| Ion Transport | 3.98 | CPLX1, SLC24A4, KCNA3, SLC6A1, RAB3A, PPP3CA, CHRNA6, GRIA3, SLC6A17, CACNB4, KCNC1, PITPNM1, CLIC4, ATP2B2, CACNG2, GRIA2, UNC13B, CALM1 |