Figure 1 of Yoo, Mol Vis 2017; 23:933-943.


Figure 1. SP blocked dispase-induced retinal damage in vivo. Intravitreal injection of dispase was performed. One and three weeks later, the retinal structure was analyzed based on histology. A: Representative micrographs showing hematoxylin and eosin staining of retinal tissue in the saline- or substance P (SP)–treated groups at 1 week post-dispase injection. B,C: The mean number of nuclei in (B) the outer nuclear layer (ONL) and (C) the inner nuclear layer (INL) were measured. D: Hematoxylin and eosin staining of retinal tissue in the saline- or SP-treated groups at 3 weeks post-dispase injection. E,F: The mean number of nuclei in the ONL and the INL. Data are presented as mean ± the standard deviation (SD). Asterisk: rosette and folding structure. Scale bar: 50 μm. The mean measurement for six images in each tissue sample was calculated for each animal. *p<0.05; **p<0.01; ***p<0.001; n=8 mice per group.