Figure 6 of Lin, Mol Vis 2017; 23:900-910.

Figure 6. A model describing the molecular mechanisms by which fisetin suppresses EGF-induced ARPE-19 cell migration. Fisetin could inhibit EGF induced the phosphorylation of AKT, thereby inhibited the EGF-induced Sp1 translocation and MMP-9 transcription activity, and further reduced migration of ARPE-19 cells.