Figure 3. Efficacy of brimonidine combined with pirenzepine on inhibiting progressing myopia. The difference in the alternation of refractive error (RE), axial length (AL), and intraocular pressure (IOP) during the experiment in groups A through F is shown. All values were calculated as the difference between the right eye and the left eye. A: RE changing course in 3 weeks. B: Histogram analysis of the difference in RE before and after the experiment. C: AL changing course in 3 weeks. D: Histogram analysis of the difference in AL before and after the experiment. E: IOP changing course in 3 weeks. F: Histogram analysis of the difference in the IOP before and after the experiment. *p<0.05 (n=6). (Group A: 2% pirenzepine group; Group B: 0.2% brimonidine group; Group C: 0.1% brimonidine group; Group D: 2% pirenzepine + 0.2% brimonidine group; Group E: 2% pirenzepine + 0.1% brimonidine group; Group F: medium group).