Figure 2. Expression of CCL2 and CCR2 in the retina after extensive light exposure. A: CCL2 was scarcely expressed in the retinal ganglion cells (RGCs) of a healthy retina. B, C: At 1 day after light exposure, there was a small amount of CCL2 expression in the outer nuclear layer (ONL), which increased in the RGCs and the inner nuclear layer (INL) at 3 days. D: At 7 days, CCL2 was observed in cells with radially oriented processes (yellow arrows) throughout the RGCs. E: CCR2 was scarcely expressed in a healthy retina. F, G: At 1 day, CCR2 was observed in the RGCs of the retina, and it was expressed robustly in the INL and the ONL at 3 days after light exposure. H: CCR2 was richly expressed in the ONL at 7 days.