Figure 6 of Wong, Mol Vis 2017; 23:718-739.


Figure 6. Expression trends. The differential status (up: U; down: D; not significant: N) for each gene marker in the list of 352 gene markers (Appendix 7, Appendix 8, Appendix 9, Appendix 10 and Appendix 11) were aligned and matched for (HV/LV) and each antioxidant [(HR/LR), (H Z+R/L Z+R), and (H A+R/L A+R)] treatment comparison. For each alignment, we scored the trend of the differential status whether they were the same or not. This information was used to derive a percent similarity measure for each antioxidant treatment under (H/L) conditions against the differential HV/LV gene profile. A goodness of fit test was performed between the percent similarities between the H/L antioxidant treatments, (HAO/LAO) comparisons with (HV/LV) to determine its statistical significance (p value). Although all three antioxidant (H/L) scenarios are all statistically significantly different than (HV/LV), the HV/LV differential gene profile is more similar to HR/LR than (H Z+R/L Z+R) or (H A+R/ L A+R).