Figure 5. Tabulation of changes induced by light rearing and antioxidant diets in retinal gene expression. Gene expression profiles
were established for different groups of animals raised with high (H) or low cyclic light rearing (L) conditions and treated
with specific dietary supplements (rosemary [R], AREDS and rosemary [A+R], or zinc oxide and rosemary [Z+R], or vehicle [V];
see
Figure 1). Differential analysis, of these profiles, was performed in three different sets of comparisons.
A: The counts of differential gene markers from comparing different antioxidant-fed L-reared animals with vehicle-fed L-reared
animals.
B: Comparison of the antioxidant-fed H-reared animals with vehicle-fed H-reared controls.
C: The findings when each dietary treatment is compared in animals reared in the high cyclic light environment with the same
treatment in animals raised in low cyclic light conditions (genes listed in Appendix 7, Appendix 8, Appendix 9, Appendix 10
and Appendix 11). In all cases, the gene markers were categorized as differentially expressed between two different treatments
if the absolute value of the fold change (FC) was ≥ 1.3, p<0.05 (|fold change (FC)|
>1.3, p<0.05).