Figure 5 of Wong, Mol Vis 2017; 23:718-739.


Figure 5. Tabulation of changes induced by light rearing and antioxidant diets in retinal gene expression. Gene expression profiles were established for different groups of animals raised with high (H) or low cyclic light rearing (L) conditions and treated with specific dietary supplements (rosemary [R], AREDS and rosemary [A+R], or zinc oxide and rosemary [Z+R], or vehicle [V]; see Figure 1). Differential analysis, of these profiles, was performed in three different sets of comparisons. A: The counts of differential gene markers from comparing different antioxidant-fed L-reared animals with vehicle-fed L-reared animals. B: Comparison of the antioxidant-fed H-reared animals with vehicle-fed H-reared controls. C: The findings when each dietary treatment is compared in animals reared in the high cyclic light environment with the same treatment in animals raised in low cyclic light conditions (genes listed in Appendix 7, Appendix 8, Appendix 9, Appendix 10 and Appendix 11). In all cases, the gene markers were categorized as differentially expressed between two different treatments if the absolute value of the fold change (FC) was ≥ 1.3, p<0.05 (|fold change (FC)| >1.3, p<0.05).