Figure 4 of Du, Mol Vis 2017; 23:707-717.


Figure 4. Enrichment of sex- and age-related changes in cell type–specific transcripts of the mouse retina. Retinal cell type–specific transcripts from previous reports [29,30] were compared to each pair-wise set of age- (A) and sex- (B) related changes, and p values were calculated using Fisher’s exact test. Dashed lines indicate significant over-representations of specific retina cell types with sex- and age-dependent changes in gene expression. C: Comparisons to disease model differential gene expression data sets demonstrate significant overlap with the age- and sex- differences observed in this study (exact hypergeometric test, Benjamini-Hochberg multiple testing correction, *p<0.05, **p<0.01, ***p<0.001).