Table 1 of
Ness, Mol Vis 2017; 23:680-694. Table 1 of
Ness, Mol Vis 2017; 23:680-694.
Table 1. List of selected genes, including the ten most up- and downregulated, from the microarray rank product (RP) analysis (≥ 2fold up- or down- regulated, q≤0.05) in multicellular tumour spheroids (MCTS) versus uncultured tumours and MCTS versus adherent cultures (see supplementary data for the complete list).
| Up in MCTS vs. uncultured tumours | Down in MCTS vs. uncultured tumours | Up in MCTS vs. adherent cultures | Down in MCTS vs. adherent cultures | ||||
|---|---|---|---|---|---|---|---|
| Gene symbol | Fold change | Gene symbol | Fold change | Gene symbol | Fold change | Gene symbol | Fold change |
| ANGPTL4 | 27.1 | HLA-DRA | -32.1 | ANGPTL4 | 21.1 | VGF | -11 |
| SSX4 | 6.4 | CD74 | -22.9 | SSX4 | 6.2 | ID3 | -10.7 |
| ASPA | 4.7 | C1QB | -17.8 | ASPA | 4.6 | MIR1974 | -5.9 |
| SSX2 | 4.5 | VWF | -14 | SSX2 | 4.3 | ILMN_1881909 | -3.9 |
| LDLR | 4.4 | CD14 | -12.2 | APOD | 3.6 | ID2 | -4.6 |
| MT1X | 4.3 | C1QC | -11.7 | IL17D | 3.2 | CTGF | -4.1 |
| HTR2B | 4.3 | HLA-DMB | -11.1 | NRXN2 | 3.2 | ID1 | -3.9 |
| FCRLA | 4.1 | HLA-DRB1 | -11.7 | MT1X | 3.1 | SRGN | -3.1 |
| SQLE | 4 | HLA-DMB | -11.1 | COL16A1 | 3 | NPTX1 | -2.8 |
| PRUNE2 | 4 | HLA-DPA1 | -10.4 | MAL | 2.8 | PENK | -2.7 |
| SLC2A10 | 3.8 | ARHGDIB | -9.7 | BMF | 2.7 | CAPS | -2.4 |
| SNAI2 | 3.5 | TYROBP | -8.7 | SSX5 | 2.7 | ODC1 | -2.3 |
| FADS1 | 2.9 | SLC15A3 | -6.4 | MT1G | 2.5 | RNU1A3 | -2.3 |
| ECH1 | 2.7 | HBA2 | -6.3 | AEBP1 | 2.5 | CYR61 | -2.3 |
| PLIN2 | 2.5 | HBB | -5.5 | CDH19 | 2.4 | LOC389342 | -2.3 |
| DHCR7 | 2.5 | ITGB2 | -5.2 | CLCNKA | 2.4 | MAL2 | -2.1 |
| OSBPL9 | 2.5 | IL18BP | -4.9 | PKNOX2 | 2.4 | CDCA7 | -2.1 |
| BMF | 2.5 | SNORD3A | -4.5 | PDK4 | 2.2 | WFDC1 | -2.1 |
| PDK4 | 2.5 | CD68 | -3.7 | MT2A | 2.2 | HSP90B1 | -2.2 |
| LSS | 2.4 | CXCL16 | -3.5 | SLC2A10 | 2.2 | IFI6 | -2.2 |
| MT2A | 2.4 | CD8A | -3.3 | GPR125 | 2.2 | LAMA1 | -2.2 |
| SC4MOL | 2.3 | CD3D | -2.7 | LSS | 2.1 | THBS2 | -2.2 |
| PECI | 2.1 | CDH1 | -2.6 | CREB1 | 2.1 | CTSL1 | -2.2 |
| MT1E | 2.1 | VCAM1 | -2.1 | MT1E | 2.1 | EIF5A | -2 |
| ACOT1 | 2 | CD2 | -2.1 | FADS1 | 2 | QPCT | -2 |