Figure 3. Volcano plot showing differentially expressed genes in the differentiated RPE cells. ARPE-19 cells grown for either 4 days
or 4 months in DMEM were used for total RNA extractions and were used for RNA-Seq analysis, as described in the Methods section.
Volcano plot for the 27,939 genes of the RPE cells cultured for 4 days and for 4 months. Representative highly up- or downregulated
genes at high statistical significance are labeled.