Table 7 of Li, Mol Vis 2017; 23:588-604.


Table 7. Association results of rs13382811 and rs6469937 in combined KORA and TwinsUK cohorts.

SNPs rs13382811 (ZFHX1B) rs6469937 (SNTB1)
Phenotype myopia (n=1088) controls (n=1335) myopia (n=1088) controls (n=1335)
Allelic Analysis            
Alleles (%) C* 1891 (86.90%) 2249 (84.23%) A* 1445 (66.41%) 1694 (63.45%)
  T 285 (13.10%) 421 (15.77%) G 731 (33.59%) 976 (36.55%)
HWE P   0.09 0.32   0.76 0.08
    P# OR§ (95%CI)   P# OR§ (95%CI)
Allelic P Values   0.0088 0.80 (0.68–0.95)   0.0319 0.88 (0.78–0.99)
Genotypic and Model Based Analysis        
Genotypes (%) CC 828 (76.10%) 952 (71.31%) AA 482 (44.30%) 552 (41.35%)
  CT 235 (21.60%) 345 (25.84%) AG 481 (44.21%) 590 (44.19%)
  TT 25 (2.30%) 38 (2.85%) GG 125 (11.49%) 193 (14.46%)
    P# OR§ (95%CI)   P# OR§ (95%CI)
Genotypic test   0.0290     0.0725  
Additive (Trend)   0.0101     0.0346  
Dominant   0.0076 0.78 (0.65–0.94)   0.1438 0.89 (0.75–1.04)
Recessive   0.3986 0.80 (0.48–1.34)   0.0314 0.77 (0.60–0.98)