Table 2 of
Li, Mol Vis 2017; 23:588-604.
Table 2. Association results of rs13382811 and rs6469937 in the Guangzhou cohort.
| SNPs | rs13382811 (ZFHX1B) | rs6469937 (SNTB1) | ||||
|---|---|---|---|---|---|---|
| Phenotype | myopia (n=300) | controls (n=308) | myopia (n=299) | controls (n=308) | ||
| Allelic Analysis | ||||||
| Alleles (%) | C | 437 (72.8%) | 504 (81.8%) | A | 136 (22.7%) | 181 (29.4%) |
| T* | 163 (27.2%) | 112 (18.2%) | G* | 462 (77.3%) | 435 (70.6%) | |
| HWE P | 0.05 | 0.05 | 0.42 | 0.35 | ||
| P# | OR§ (95%CI) | P# | OR§ (95%CI) | |||
| Allelic P Values | 0.0001 | 1.68 (1.28–2.20) | 0.0085 | 0.71 (0.55–0.92) | ||
| Genotypic and Model Based Analysis | ||||||
| Genotypes (%) | CC | 166 (55.3%) | 201 (65.3%) | AA | 13 (4.3%) | 30 (9.7%) |
| CT | 105 (35.0%) | 102 (33.1%) | AG | 110 (36.8%) | 121 (39.3%) | |
| TT | 29 (9.7%) | 5 (1.6%) | GG | 176 (58.9%) | 157 (51.0%) | |
| P# | OR§ (95%CI) | P# | OR§ (95%CI) | |||
| Genotypic test | 4.07×10−5 | 0.0166 | ||||
| Additive (Trend) | 0.0002 | 0.0090 | ||||
| Dominant | 0.0124 | 1.52 (1.09–2.10) | 0.0509 | 0.73 (0.53–1.00) | ||
| Recessive | 1.59×10−5 | 6.48 (2.48–16.99) | 0.0096 | 0.42 (0.22–0.82) | ||