FB ASOs were electroporated to mouse primary hepatocytes. Cells were harvested 16 h after electroporation total cellular RNA was isolated, and the amount of FB mRNA was quantified using a quantitative qRT-PCR) assay. Values are presented as % of untreated control (UTC). The arrow is pointing to ION-516323 ASO that was selected for the in vivo studies. To access the data, click or select the words “Appendix 1”.