Figure 1. mRNA expression of kynurenine aminotransferases in the cornea, conjunctiva, and retina. Expression of (
A) KAT I (the
KYAT1 gene), (
B) KAT II (the
AADAT/KYAT2 gene), (
C) KAT III (the
KYAT3 gene), and (
D) KAT IV (the
GOT2 gene) in the cornea (n = 10), conjunctiva (n = 27), and retina (n = 17). Previously described [
44-
46] microarray data were obtained from the Gene Expression Omnibus (GEO) database (accession numbers: GSE29402, GSE38190, GSE28133,
and GSE20436) using Genevestigator software. The Kruskal–Wallis test and Dunn’s post hoc test were used to statistically evaluate
the differences in gene expression between the tissues of interest. *** p<0.001; n/s., not significant.