Table 5 of Liao, Mol Vis 2017; 23:318-333.

Table 5. Single tissue significant cis-eQTLs for AMD-associated SNPs rs10490924.

Gencode ID Gene Symbol P-Value Effect Size Tissue
ENSG00000254636.1 ARMS2 7.50E-24 −0.79 Testis
ENSG00000107679.10 PLEKHA1 1.40E-08 −0.25 Nerve - Tibial
ENSG00000166033.7 HTRA1 1.50E-07 0.4 Testis
ENSG00000254636.1 ARMS2 7.00E-07 −0.46 Skin - Sun Exposed (Lower leg)

The table provides the results from a search of GTEx for the entire list of genes that are influenced by the reference SNP rs10490924 using the GTEx default criteria for significance. Note that only 3 genes appear, indicating that no other gene anywhere in chromosome 10q26 nor any gene in the GTEx database throughout the human genome is influenced by the reference SNP. Similar results appear for all of the 25 GTEx SNPs in the AMD-risk haplotype (data not shown), as expected since they are all in strong linkage disequilibrium.

Liao, Mol Vis 2017; 23:318-333. http://www.molvis.org/molvis/v23/318

©2017 Molecular Vision http://www.molvis.org/molvis/

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