Table 4 of Liao, Mol Vis 2017; 23:318-333.


Table 4. The rs10490924-T allele is associated with low levels (positive effect sizes) of HTRA1 gene expression in most tissues.

Tissue P-Value Effect Size Expression (Mean RPKM) Number Samples
Testis 1.50E-07 0.4 12.333 157
Pituitary 0.016 0.28 105.377 87
Artery - Coronary 0.043 0.16 144.948 118
Artery - Aorta 0.017 0.13 268.567 197
Liver 0.12 0.12 52.72 97
Breast - Mammary Tissue 0.074 0.11 114.907 183
Whole Blood 0.029 0.1 1.153 338
Lung 0.032 0.098 36.291 278
Adipose - Subcutaneous 0.056 0.094 126.917 298
Small Intestine - Terminal Ileum 0.24 0.093 21.23 77
Vagina 0.12 0.09 96.109 79
Adrenal Gland 0.36 0.082 36.291 126
Nerve - Tibial 0.26 0.077 99.2 256
Colon - Transverse 0.074 0.066 36.749 169
Spleen 0.45 0.06 26.428 89
Brain - Hippocampus 0.63 0.051 129.512 81
Heart - Atrial Appendage 0.44 0.043 30.707 159
Thyroid 0.32 0.039 42.25 278
Esophagus - Mucosa 0.46 0.032 14.493 241
Muscle - Skeletal 0.34 0.026 6.046 361
Skin - Sun Exposed (Lower leg) 0.64 0.019 62.815 302
Artery - Tibial 0.78 0.01 139.083 285
Adipose - Visceral (Omentum) 0.86 0.0092 110.21 185
Heart - Left Ventricle 0.88 0.0084 21.246 190
Brain - Nucleus accumbens (bg) 0.97 0.0036 132.309 93
Pancreas 0.98 0.0024 14.597 149
Ovary 0.99 0.0012 211.834 85
Stomach 0.78 −0.012 20.678 170
Brain - Hypothalamus 0.83 −0.026 101.534 81
Brain - Cortex 0.68 −0.03 118.249 96
Brain - Caudate (basal ganglia) 0.68 −0.037 188.491 100
Brain - Anterior cingulate cortex (BA24) 0.29 −0.069 141.737 72
Esophagus - Muscularis 0.13 −0.081 53.302 218
Colon - Sigmoid 0.29 −0.089 74.374 124
Brain - Frontal Cortex (BA9) 0.21 −0.092 116.804 92
Brain - Cerebellum 0.18 −0.099 44.175 103
Skin - Not Sun Exposed (Suprapubic) 0.12 −0.1 60.731 196
Brain - Putamen (basal ganglia) 0.18 −0.1 193.492 82
Brain - Cerebellar Hemisphere 0.15 −0.12 28.95 89
Uterus 0.073 −0.21 104.586 70
Prostate 0.017 −0.23 37.874 87