Figure 4. RvD1 alleviated the phosphorylation of NF-κB and degradation of IκBα in the retinas of STZ-treated rats. A: Western blot analysis of the nuclear factor kappa beta (NF-κB) phosphorylation in the retinas of diabetic rats with or without the treatment of resolvin D1 (RvD1). B: The levels of NF-κB phosphorylation were increased in the retinas of diabetic rats compared with the control group, while the increase was statistically significantly blocked in the RvD1 group. C: Western blot analysis of the degradation of IκBα in the retinas of diabetic rats with or without the treatment of RvD1. D: Enhanced degradation of IκBα in the retinas of diabetic rats was blocked by RvD1. Each column denotes the mean ± standard deviation (SD); n = 6. * p<0.05, **p<0.01, *** p<0.001.