Figure 4. β-Dystroglycan (βDys) distribution. A: In wild-type (WT) samples, βDys localizes to the basal side of epithelial cells and on fiber membranes. The strongest βDys signals have a connexin (Cx)-like staining pattern on fiber membranes. B: In WT inner cortical fibers, βDys displayed Cx-like staining. C: In knock-in (Ki) samples, βDys is similar to WT samples in peripheral fibers, but lacks Cx-like staining. D: In Ki inner cortical fibers, βDys was undetectable. Scale bars: 5 μm.