Table 2 of
Xu, Mol Vis 2017; 23:1081-1092. Table 2 of
Xu, Mol Vis 2017; 23:1081-1092.
Table 2. The list of highly influenced ingenuity canonical pathways.
| Ingenuity Canonical Pathways | P value | Ratio | Molecules | |
|---|---|---|---|---|
| Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 0.0019 | 5/106 | (0.047) | OAS1, IRF7, DDX58, C3AR1, Oas1b |
| Complement System | 0.0024 | 3/35 | (0.086) | MASP2, C1S, C3AR1 |
| Interferon Signaling | 0.0027 | 3/36 | (0.083) | OAS1, IRF9, IFIT3 |
| Activation of IRF by Cytosolic Pattern Recognition Receptors | 0.0117 | 3/72 | (0.042) | IRF9, IRF7, DDX58 |
| Ethanol Degradation IV | 0.0129 | 2/29 | (0.069) | TYRP1, ALDH3A1 |
| Communication between Innate and Adaptive Immune Cells | 0.0200 | 3/109 | (0.028) | HLA-B, IL15, B2M |
| LXR/RXR Activation | 0.0204 | 4/136 | (0.029) | PON1, VTN, SCD, TTR |
| Superpathway of Cholesterol Biosynthesis | 0.0257 | 2/87 | (0.023) | IDI1, HSD17B7 |
| Trans, trans-farnesyl Diphosphate Biosynthesis | 0.0288 | 1/10 | (0.100) | IDI1 |
| Antigen Presentation Pathway | 0.0295 | 2/40 | (0.050) | HLA-B, B2M |