Table 1 of
Li, Mol Vis 2017; 23:1048-1080. Table 1 of
Li, Mol Vis 2017; 23:1048-1080.
Table 1. Loci identified by linkage studies.
| Phenotype | Location | MIM number | Size(Mb) | Lod Score | Study poplution | Reference |
|---|---|---|---|---|---|---|
| adHM | ||||||
| MYP2 | 18p11.31 | 160,700 | 7.6-cM | 9.59 | USA | (Young TL et al., 2001) |
| MYP3 | 12q21-q23 | 603,221 | 30.1-Cm | 3.85 | German/Italian | (Young TL et al., 1998) |
| MYP5 | 17q21-q22 | 608,474 | 7.71-cM | 3.17 | English/Canadian | (Paluru P et al., 2003) |
| MYP11 | 4q22-q27 | 609,994 | 20.4-cM | 3.11 | Chinese | (Zhang Q et al., 2005) |
| MYP12 | 2q37.1 | 609,995 | 9.1 cM | 4.75 | Northern European | (Paluru PC et al., 2005) |
| MYP15 | 10q21.1 | 612,717 | 2.67 cM | 3.22 | Hutterite | (Nallasamy S, 2007) |
| MYP16 | 5p15.33-p15.2 | 612,554 | 17.45Mb | 4.81 | Chinese | (Lam CY et al., 2008) |
| MYP17 | 7p15 | 608,367 | 7.81 cM | NA | France | (Paget et al., 2008) |
| MYP19 | 5p15.1-p13.3 | 613,969 | 14.14-Mb | 3.71 | Chinese | (Ma et al., 2010) |
| arHM | ||||||
| MYP18 | 14q22.1-q24.2 | 255,500 | 25.23-Mb | 2.19 | Chinese | (Yang et al., 2009) |
| X-linked HM | ||||||
| MYP1 | Xq28 | 310,460 | 6.1cM | 3.59 | Chinese | (Guo et al., 2010) |
| MYP13 | Xq23-q27.2 | 300,613 | 25-cM | 2.75 | Chinese | (Zhang et al., 2006) |
| Complex myopia | ||||||
| MYP6 | 22q12.3 | 608,908 | 4cM | 3.54 | Ashkenazi Jewish | (Stambolian et al., 2004) |
| MYP7 | 11p13 | 609,256 | 40cM | 6.1 | UK | (Hammond et al., 2004) |
| MYP8 | 3q26 | 609,257 | 185cM | 3.7 | UK | (Hammond et al., 2004) |
| MYP9 | 4q12 3.3 | 609,258 | 65cM | 3.3 | UK | (Hammond et al., 2004) |
| MYP10 | 8p23 | 609,259 | NA | 3.7 | UK | (Hammond et al., 2004) |
| MYP14 | 1p36 | 610,320 | 49.1 Cm | 9.5 | Ashkenazi Jewish | (Wojciechowski et al., 2006) |