Figure 4. Epac1 regulates NFκB phosphorylation in the mouse retina. Whole retinal lysates from exchange protein for cAMP 1 (Epac1) floxed versus Epac1 Cre-Lox mice were processed for western blot analyses for phosphorylated nuclear factor kappa beta (NFκB (Ser536) versus total NFκB (A) or inhibitor of kappa beta (IκB; B). n = 5 for each group. Data are mean ± standard error of the mean (SEM). *p<0.05 versus Epac1 floxed.