Figure 5. Failure of PI3Kγ^−/− cells to migrate in reconstructed cornea system. Under conditions when 65% of wild-type cells plated onto wild-type corneas de-epithelialized by scraping successfully migrate, only 20% of cells do so in the presence of β1 integrin blocking antibody. Almost no PI3Kγ^−/− cells migrate, whether plated onto wild-type or PI3Kγ^−/− corneas. Abbreviation: MCE; mouse corneal epithelial cells.