Table 4 of Tang, Mol Vis 2016; 22:917-932.
Group | Phenotypes | N. | Age at diagnosis | Gender M(M%) | N. of pathogenic FZD4 mutations |
---|---|---|---|---|---|
I: Mild | Bilateral asymptomatic but confirmed by FFA | 10(10.0%) | 44.0±15.1 | 4(40.0%) | 0 |
II: Moderate | Vitreous hemorrhage due to RNV* | 4(4.0%) | 25.3±12.3 | 2(50.0%) | 1 |
III: Severe | Retinal folding or ectopic macula* | 69(69.0%) | 9.2±10.3 | 57(82.6%) | 20 |
IV: Extreme severe | Total tractional RD in infancy* | 17(17.0%) | 2.0±2.3 | 14(82.3%) | 0 |
P value | - | - | <0.001∆ | 0.012§ | - |
Total | 100(100%) | 12.1±15.3 | 77(77.0%) | 21 |