Figure 1 of Tang, Mol Vis 2016; 22:917-932.

Figure 1. Types and locations of novel mutations. A: Schematic diagram of the FZD4 gene. B: The Frizzled 4 protein shows the types and locations of the novel mutations. The locations of the transmembrane domain were derived from GenBank entry Q9ULV1. The first 36 amino acids (◇) were a Frizzled-4 signal peptide.