Figure 1. Differential mean ± SEM mRNA expression of metabolism-related genes in mature mouse retina. A doubling of the amount of mRNA
is considered a twofold change. A: Hk1 and Hk2 showed greater than twofold higher expression when compared to Hk3 and glucokinase (Gk). Isoforms l, m and p of Pfk showed similar levels of expression. Pkm showed greater than twofold higher expression compared to isoforms Pklr. To enhance readability, the protein isoform number appears under the gene name of each Ldh isoform. Ldh isoforms a (LDH-5, skeletal muscle) and b (LDH-1, heart) showed greater than twofold higher expression compared to the isoforms c (LDH-3) and d (LDH-4). Cox4i isoform 1 is expressed greater than twofold higher than Cox4i2. B: Several Nme isoforms are expressed in the retina, with Nme1 and Nme2 showing the highest relative expression. Genes of isoforms 1–3 and 5 of Ak showed similar expression. Ckb showed greater than twofold higher expression compared to Ckm, and CK-mt1 showed greater than twofold higher expression compared to Ck-mt2.
![](mv-v22-847-f1.jpg)