Figure 1. Pedigree and haplotype for four consanguineous Tunisian families who segregate Usher type 1. In the pedigree, the square symbol indicates male, the circle symbol denotes female, and the black squares represent affected individuals. Linkage analysis performed on all families showed that two were linked to USH1B, and the remaining families with USH1 were linked to USH1C and USH1F.