Figure 5. ERGs for healthy and I/R-injured retinas. A: Representative electroretinograms (ERGs) from healthy retinas and ischemia/reperfusion (I/R)-injured retinas treated with no vehicle, mutant (triple Y-F) self-complementary adeno-associated virus type 2 vector encoding green fluorescent protein (tm-scAAV2-GFP), or tm-scAAV2-brain-derived neurotrophic factor (BDNF). B: b-wave amplitudes 6 days after ischemia. Bars depict means ± standard deviation (SD). There was no statistical difference in the b-waves between the normal retinas (n = 8) and the tm-scAAV2-BDNF-treated retinas (n = 6; p>0.05). The tm-scAAV2-BDNF-treated retinas were significantly protected compared to the no vehicle (n = 8; **p<0.01) and tm-scAAV2-GFP (n = 3; **p<0.01) groups.