Figure 2. BDNF gene and protein expression. Relative levels of the brain-derived neurotrophic factor (BDNF) mRNA (ratio of brain-derived BDNF/GAPDH) (A) and protein (B) were significantly increased in the neurosensory retinas of rats treated with mutant (triple Y-F) self-complementary adeno-associated virus type 2 vector encoding BDNF (tm-scAAV2-BDNF). n = 6 in each group. Bars depict means ± standard deviation (SD).