Table 1. Stochastic R* parameters.
| Symbol |
Description |
Value |
Units |
|
Model 1: Conventional graded R* shut-off |
|
|
| N |
Number of sites for phosphorylation |
6 |
|
| M |
Minimum phosphates for Arr binding |
3 |
|
| νmax |
Maximal rate constant of phosphorylation |
80 |
s−1 |
| μ |
Rate constant of Arr binding |
20 |
s−1 |
| ωP |
Exponential factor for phosphorylation |
1 |
|
| ωG |
Exponential factor for R* activity |
1 |
|
|
Model 2: Binary R* shut-off
Case 1: All rate constants equal |
|
|
| N |
Number of sites for phosphorylation |
Any, ≥3 |
|
| M |
Minimum phosphates for Arr binding |
3 |
|
| ν, μ |
Rate constants for all reactions |
60 |
s−1 |
|
Model 3: Three-state R* shut-off
Case 1: All rate constants equal |
|
|
| N |
Number of sites for phosphorylation |
Any, ≥3 |
|
| M |
Minimum phosphates before Arr binding |
3 |
|
| ν, κ, μ |
Rate constants for all reactions |
60 |
s−1 |
| ρlow |
Fractional R* activity in low-activity state |
0.1 |
|
Table 1 of
Lamb, Mol Vis 2016; 22:674-696.