Figure 2. SAS and LM609 significantly increase PEDF mRNA levels in the RPE-EC co-culture system. RT–PCR analysis of VEGF (A) and PEDF (B) mRNA levels in pure mono-cultures of RPE alone (solo RPE) and co-cultures of RPE-EC cells (co-culture). *p<0.05 decreased relative to solo RPE; ** p<0.05 increased relative to RPE co-cultured with ECs. Results shown are mean ± SD.