Table 3 of Jones, Mol Vis 2016; 22:472-490.

Table 3. Ingenuity pathway analysis (IPA) of differential gene expression lists.

Gene List Canonical Pathway -log(p-value) z-score Gene IDs
RCSsham vs. LEsham Upregulated Integrin Signaling 3.79 4.123 ACTA1, ACTB, ARPC1B, ITGA6, ITGA9, ITGAL, ITGAM, ITGB2, PARVA, PIK3CG, RAC2, RAP2B, RHOB, RHOC, RHOJ, RRAS, SRC, TSPAN4
RCShNPCs vs. RCSsham Downregulated Integrin Signaling 1.54 -2.000 ARPC1A, PARVA, RHOB, RRAS
RCSsham vs. LEsham Upregulated Phospholipase C Signaling 2.14 3.606 BLNK, FCER1G, FCGR2A, FCGR2B, GNB3, GNG5SRC, LYN, PLCE1, PLD4, RHOB, RHOC, RHOJ, RRAS, SYK, TGM
RCShNPCs vs. RCSsham Downregulated Phospholipase C Signaling 1.31 -2.000 GNG5, PLA2G1B, RHOB, RRAS
RCSsham vs. LEsham Upregulated Signaling by Rho Family GTPases 2.6 3.873 ACTA1, ACTB, ARPC1B, CDC42EP5, CDH11, EZR, FOX, GFAP, GNB3, GNG5, JUN, MSNRHOC, PIK3CG, RHOB, RHOJ, SEPT10
RCShNPCs vs. RCSsham Downregulated Signaling by Rho Family GTPases 1.94 -2.000 ARPC1A, CDC42EP5, GFAP, GNG5, RHOB

Upregulated RCSsham versus LEsham and downregulated RCShNPCs versus RCSsham gene lists were compared. Significance was determined at –log p value ≥1.31 and z-score ≥2 or ≤ −2. Gene IDs shown are those that were found to be differentially expressed in the data set as determined by IPA software (QIAGEN, Redwood City).

Jones, Mol Vis 2016; 22:472-490. http://www.molvis.org/molvis/v22/472

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