Figure 3. Comparison of differentially expressed gene sets reveals the presence of rescue genes. Up- and downregulated differentially
expressed gene sets were determined for retinal degenerate Royal College of Surgeons (RCSsham) rats versus wild-type Long Evans (LEsham) rats and Royal College of Surgeons rats with a subretinal injection of human forebrain derived neural progenitor cells (RCShNPCs) rats versus RCSsham rats and compared for overlapping genes. Genes with inverse relationships between the gene sets, termed rescued genes, were
identified (circle and square).