Figure 3. Comparison of differentially expressed gene sets reveals the presence of rescue genes. Up- and downregulated differentially expressed gene sets were determined for retinal degenerate Royal College of Surgeons (RCS^sham) rats versus wild-type Long Evans (LE^sham) rats and Royal College of Surgeons rats with a subretinal injection of human forebrain derived neural progenitor cells (RCS^hNPCs) rats versus RCS^sham rats and compared for overlapping genes. Genes with inverse relationships between the gene sets, termed rescued genes, were identified (circle and square).