Table 4 of
Akin, Mol Vis 2016; 22:40-60. Table 4 of
Akin, Mol Vis 2016; 22:40-60.
Table 4. Gene Ontology of genes downregulated in response to PNN reduction.
| GO term | Description | P-value | FDR q-value | Enrichment | Genes |
|---|---|---|---|---|---|
| Biologic Process | |||||
| GO:0044283 | small molecule biosynthetic process | 3.65E-06 | 4.26E-03 | 2.41 | SLC1A3, MNGCR, EBP, DHCR7,CYP51A1, FADS2, PADI2, HMGSC1 |
| GO:1901624 | negative regulation of lymphocyte chemotaxis | 9.55E-06 | 9.28E-03 | 57.75 | KLRK1, CCL2, PADI2 |
| GO:0002376 | immune system process | 3.52E-05 | 2.28E-02 | 1.37 | UBD, CFI, RPS24, CLEC7A, IFITM2, ADCY5, IL7R, KITLG |
| GO:2000402 | negative regulation of lymphocyte migration | 5.61E-05 | 3.27E-02 | 43.31 | CCL2, PADI2, KLRK1 |
| GO:0045595 | regulation of cell differentiation | 5.94E-05 | 3.30E-02 | 1.41 | IGFBP5, IL7R, KITLG |
| GO:0050793 | regulation of developmental process | 9.10E-05 | 4.82E-02 | 1.33 | FGD3, IGFB5, COLQ, HMGCR, |
| GO:0032808 | lacrimal gland development | 9.85E-05 | 5.00E-02 | 16.49 | RARG, FGFR2, PAX6, SOX10 |