Table 2 of
Akin, Mol Vis 2016; 22:40-60. Table 2 of
Akin, Mol Vis 2016; 22:40-60.
Table 2. Genes downregulated in response to PNN reduction.
| Gene symbol | P-adj | Log2FoldChange | Gene name |
|---|---|---|---|
| ABCA4 | 2.33E-15 | −2.14 | ATP-binding cassette, sub-family A (ABC1), member 4 |
| ABCA4 | 3.78E-14 | −2.46 | ATP-binding cassette, sub-family A (ABC1), member 4 |
| FGD3 | 1.50E-09 | −2.02 | FYVE, RhoGEF and PH domain containing 3 |
| INSL4 | 2.80E-06 | −1.82 | insulin-like 4 (placenta) |
| IGFL1 | 4.07E-06 | −1.68 | IGF-like family member 1 |
| IGFBP5 | 3.46E-05 | −2.05 | insulin-like growth factor binding protein 5 |
| VGLL1 | 3.46E-05 | −1.85 | vestigial-like family member 1 |
| PNN | 3.46E-05 | -1.14 | pinin |
| UBD | 3.99E-05 | −1.77 | ubiquitin D |
| CFI | 9.25E-05 | −1.61 | complement factor I |
| PCSK9 | 9.25E-05 | −1.27 | proprotein convertase subtilisin/kexin type 9 |
| SLC1A3 | 0.00024818 | −1.04 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| DHRS3 | 0.00057796 | −1.28 | dehydrogenase/reductase (SDR family) member 3 |
| VGLL1 | 0.00132719 | −1.65 | vestigial-like family member 1 |
| CDH5 | 0.00132719 | −1.49 | cadherin 5, type 2 (vascular endothelium) |
| RPS24 | 0.00133766 | −0.99 | ribosomal protein S24 |
| LINC01559 | 0.00180566 | −1.05 | long intergenic non-protein coding RNA 1559 |
| RPS24 | 0.00238888 | −0.94 | ribosomal protein S24 |
| CLEC7A | 0.00263968 | −1.49 | C-type lectin domain family 7, member A |
| RARRES3 | 0.00294625 | −1.07 | retinoic acid receptor responder (tazarotene induced) 3 |