Figure 2. Xaliproden protects against the loss of tight junctions in the presence of paraquat. ARPE-19 cells were seeded in 24 Transwell plates and grown in low serum medium for 2 weeks. The cells were then treated with paraquat (300 µM), xaliproden (20 µM), or a combination of the two for 24 h before the transepithelial resistance (TEER) was measured in a volt/ohm meter. Bars represent the average electrical resistance from triplicates ± standard deviation (SD). *, p = 0.006 between paraquat, and paraquat + xaliproden, as determined with one-way ANOVA. Par = paraquat; Xali = xaliproden.