Deletion of Sod2 leads to extensive vacuolization of the RPE that is mitigated by treatment with xaliproden. A. Retinal hemisphere from a vehicle-treated mouse. B. retina from a mouse treated with 3 mg/kg of xaliproden. Plastic sections (1 μM) were stained with toluidine blue. Original magnification was 40X. Insets are electronically magnified regions from the posterior retinas. To access the data, click or select the words “Appendix 5.”