Table 1 of Xu, Mol Vis 2016; 22:275-283.

Table 1. Summary analysis of rhythmicity for retinal and Müller cell preparations.

Preparation Period (h) Power Goodness (%) N
Per2::Luc MMC 24.05±0.11 0.170±0.121 27.616±12.00 6
MMC with Per2::Luc lentivirus 22.67±2.11 0.163±0.114 15.07±4.53 4
MMC with Bmal1::Luc lentivirus 23.98±0.12 0.147±0.105 23.86±9.22 7
Per1::Luc Retina 24.1±3.89 0.197±0.20 20.42±13.64 6
Per1−/−/Per2::Luc Retina ns 0.010±0.008 8.98±5.60 3
Per1−/−/Per2::Luc MMC ns 0.032±0.018 20.57±4.47 3
Bmal1−/− Per2::Luc Retina ns 0.0087±0.0089 17.87±6.27 3
Bmal1−/− Per2::Luc MMC ns 0.051±0.039 8.31±1.96 3
Per1::Luc MMC ns 0.00034±0.000016 15.45±0.99 4
Per2::Luc MMC with control siRNA 23.99±0.12 0.193±0.171 25.85±22.78 4
Per2::Luc MMC with lipofectamine 23.96 0.26 29.8 1
Per2::Luc MMC with Per1 siRNA ns 0.032±0.007 9.19±1.06 2
Per2::Luc MMC with Per2 siRNA ns 0.0172±0.018 4.055±3.31 2
Per2::Luc MMC with Bmal1 siRNA ns 0.006±0.004 0.02±0.66 4
HMC with Per2::Luc lentivirus 23.32±1.51 0.474±0.076 54.2±9.37 5
HMC with Per2::Luc lentivirus control siRNA 22.87±1.95 0.45±0.072 55.8±9.47 3
HMC with Per2::Luc lentivirus lipofectamine 22.37±2.48 0.43±0.014 52.65±13.93 2
HMC with Per2::Luc lentivirus Per1 siRNA 22.87±1.96 0.16±0.107 20.99±10.97 3
HMC with Per2::Luc lentivirus Per2 siRNA 24.03±0.099 0.396±0.104 42.68±9.53 5
HMC with Per2::Luc lentivirus Bmal1 siRNA ns 0.035±0.050 12.5±2.36 3

Effects on rhythmicity were quantified using Lumicycle software with the threshold for rhythmicity set at an average rhythmic power of ≥0.1 and goodness of fit ≥15% [30]. Values are reported as mean ± standard deviation. Period in hours is shown for those preparations that met the criteria for rhythmicity. MMC=mouse Müller cells; HMC=human Müller cells.

Xu, Mol Vis 2016; 22:275-283. http://www.molvis.org/molvis/v22/275

©2016 Molecular Vision http://www.molvis.org/molvis/

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