Figure 4. LFE up-regulates Beclin-1, LC3-I and LC3-II expression in HSV-1 infected SIRC cells. Cells pretreated with 0.05, 0.1 or 0.2 μg/ml of LFE for 1.5 h then infected with HSV-1 at 1 MOI for 24 h. The protein levels were normalized against the β-actin signal. Bars are means ± standard error of the mean (SEM). A, B, C, D: bars with different letters differed (p<0.05).